So here is what happened in 1918 during the Spanish Flu Pandemic--

By the end of the season, nearly 20 percent of all major football teams had shuttered their programs for the season. The Missouri Valley Conference, the forerunner to the Big 8 and Big 12, closed down completely as all seven of its member schools decided not to play football in the midst of the pandemic. In total, 16 of the 88 major programs of the period were sidelined by the Spanish flu.

The season also resulted in truncated schedules. In 1917, the median college football season lasted eight games. A year later, teams cut their schedules nearly in half as teams played on average five games that season. Where Georgia Tech went 9-0-0 to win the 1917 national championship, Michigan went just 5-0-0 and Pitt 4-1-0 as the Wolverines and Panthers split the spoils.

This the article that discusses the 1918 college season and how it might play out in 2020.

https://saturdayblitz.com/2020/03/22/col...-pandemic/