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CrimsonPhantom Offline
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DNA Data Storage Is About To Go Viral
Quote:In 1862, Gregor Mendel bred pea plants to study inheritance. Fast forward 100 years to 1962, James Watson, Frances Crick, and Maurice Wilkins were awarded a Nobel Prize for discovering the structure of DNA. Today, advances in this field are spilling over into the most unlikely places.

As we enter the century of biotechnology, our ability to read, write, and edit DNA is disrupting everything from human health to manufacturing. The next disruption to take place could be in the world of data storage.

Tech giants including Facebook and Amazon and their millions of users generate petabytes of data on the Internet every second. Microsoft has been quietly working in the background to store this information in As, Ts, Cs, and Gs, instead of 0s and 1s.


“Think of compressing all the information on the accessible Internet into a shoebox,” says Karin Strauss, a principal researcher at Microsoft. “With DNA data storage, that’s possible.”

Strauss is working with Luis Ceze, a professor of computer science and engineering at the University of Washington, to wield DNA for data storage and computing. Using synthetic DNA molecules, the team has successfully stored over one gigabyte of readable information, including various forms of media such as the top 100 books from Project Gutenberg, a high-definition OK Go music video, and the #MemoriesInDNA project.

The information density of DNA is remarkable — just one gram can store 215 petabytes, or 215 million gigabytes, of data. For context, the average hard drive in a laptop can house just one millionth of that amount.

“We encode all data at a molecular level, making it as small as possible, and store it in a medium that will last for quite a while and not become obsolete, like floppy disks, because of its eternal relevance for life,” says Strauss.

In addition to pioneering high-density data storage, Ceze and Strauss also conducted a similarity search between images using DNA, and recently created the first fully-automated, writing-to-reading DNA storage system.

“We’re trying to make computers better with a systematic approach that finds great alternatives and solutions in nature,” says Strauss. “The computational approaches facilitated by working with DNA make it an even more attractive option for data storage,” adds Ceze. “We have the freedom to choose how to map bits to DNA sequences, creating redundancy and high tolerance to error when reading and writing DNA.”

How does this technology work? It’s surprisingly simple. Data is first translated from a code of 0s and 1s to As, Ts, Cs, and Gs. This genetic code is then synthesized into an actual molecule (with the help of Twist Bioscience for the Microsoft Research-UW team), and the “encoding” process is complete.

Retrieving data is a bit more complex. Two steps — “processing” and “decoding” — must occur. Simulating random-access memory (RAM), a polymerase chain reaction (PCR, a common laboratory protocol for copying DNA) hones in on a targeted section of the sequence, which is then replicated, sequenced, decoded, and adjusted for errors to retrieve the original data. This targeted approach is efficient because it involves only the desired sequence, rather than the entire dataset.

The rise of DNA data storage, previously the stuff of science fiction, is being made possible by advances in biotechnology, particularly improvements in high-throughput DNA sequencing and synthesis. Also, because these bio-programmers control what materials enter their experiments, and their sequences do not need to be meticulously engineered to function within a living organism, there are fewer overhead costs compared to typical life science experiments. The journey has not been without roadblocks, however. Despite dramatic improvement, working with DNA can be slow and expensive. Further streamlining is still needed.

“Automation was, and is, one of our biggest challenges,” says Strauss. “It was great to have our first proof of concept converting information from bits, to DNA, and back to bits to prove that it was possible and also show what are our other challenges in automation, but some of the biotechnology aspects are quite new to some of us, so we’ve also been learning a lot there. The other significant challenges are continuing to increase throughput and decrease the cost for DNA sequencing and synthesis. There’s quite a bit of engineering left to get [us] to where we need to be.”

The interdisciplinary Microsoft and UW team sees value in its diverse background. “It’s extremely exciting that this is at the intersection of biotech and computing,” says Ceze. “These areas have been feeding off each other.”

“If the technology continues to advance the way we see it right now,” he says, “I think it’s conceivable that we will see DNA storage as a form of archival for the general public within the decade.”

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06-05-2021 09:28 AM
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TigerBlue4Ever Offline
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Post: #2
RE: DNA Data Storage Is About To Go Viral
What a bizarre world, nay, universe, nay, existence we inhabit. I understood very little of that.
06-05-2021 10:18 AM
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shere khan Offline
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RE: DNA Data Storage Is About To Go Viral
(06-05-2021 09:28 AM)CrimsonPhantom Wrote:  
Quote:In 1862, Gregor Mendel bred pea plants to study inheritance. Fast forward 100 years to 1962, James Watson, Frances Crick, and Maurice Wilkins were awarded a Nobel Prize for discovering the structure of DNA. Today, advances in this field are spilling over into the most unlikely places.

As we enter the century of biotechnology, our ability to read, write, and edit DNA is disrupting everything from human health to manufacturing. The next disruption to take place could be in the world of data storage.

Tech giants including Facebook and Amazon and their millions of users generate petabytes of data on the Internet every second. Microsoft has been quietly working in the background to store this information in As, Ts, Cs, and Gs, instead of 0s and 1s.


“Think of compressing all the information on the accessible Internet into a shoebox,” says Karin Strauss, a principal researcher at Microsoft. “With DNA data storage, that’s possible.”

Strauss is working with Luis Ceze, a professor of computer science and engineering at the University of Washington, to wield DNA for data storage and computing. Using synthetic DNA molecules, the team has successfully stored over one gigabyte of readable information, including various forms of media such as the top 100 books from Project Gutenberg, a high-definition OK Go music video, and the #MemoriesInDNA project.

The information density of DNA is remarkable — just one gram can store 215 petabytes, or 215 million gigabytes, of data. For context, the average hard drive in a laptop can house just one millionth of that amount.

“We encode all data at a molecular level, making it as small as possible, and store it in a medium that will last for quite a while and not become obsolete, like floppy disks, because of its eternal relevance for life,” says Strauss.

In addition to pioneering high-density data storage, Ceze and Strauss also conducted a similarity search between images using DNA, and recently created the first fully-automated, writing-to-reading DNA storage system.

“We’re trying to make computers better with a systematic approach that finds great alternatives and solutions in nature,” says Strauss. “The computational approaches facilitated by working with DNA make it an even more attractive option for data storage,” adds Ceze. “We have the freedom to choose how to map bits to DNA sequences, creating redundancy and high tolerance to error when reading and writing DNA.”

How does this technology work? It’s surprisingly simple. Data is first translated from a code of 0s and 1s to As, Ts, Cs, and Gs. This genetic code is then synthesized into an actual molecule (with the help of Twist Bioscience for the Microsoft Research-UW team), and the “encoding” process is complete.

Retrieving data is a bit more complex. Two steps — “processing” and “decoding” — must occur. Simulating random-access memory (RAM), a polymerase chain reaction (PCR, a common laboratory protocol for copying DNA) hones in on a targeted section of the sequence, which is then replicated, sequenced, decoded, and adjusted for errors to retrieve the original data. This targeted approach is efficient because it involves only the desired sequence, rather than the entire dataset.

The rise of DNA data storage, previously the stuff of science fiction, is being made possible by advances in biotechnology, particularly improvements in high-throughput DNA sequencing and synthesis. Also, because these bio-programmers control what materials enter their experiments, and their sequences do not need to be meticulously engineered to function within a living organism, there are fewer overhead costs compared to typical life science experiments. The journey has not been without roadblocks, however. Despite dramatic improvement, working with DNA can be slow and expensive. Further streamlining is still needed.

“Automation was, and is, one of our biggest challenges,” says Strauss. “It was great to have our first proof of concept converting information from bits, to DNA, and back to bits to prove that it was possible and also show what are our other challenges in automation, but some of the biotechnology aspects are quite new to some of us, so we’ve also been learning a lot there. The other significant challenges are continuing to increase throughput and decrease the cost for DNA sequencing and synthesis. There’s quite a bit of engineering left to get [us] to where we need to be.”

The interdisciplinary Microsoft and UW team sees value in its diverse background. “It’s extremely exciting that this is at the intersection of biotech and computing,” says Ceze. “These areas have been feeding off each other.”

“If the technology continues to advance the way we see it right now,” he says, “I think it’s conceivable that we will see DNA storage as a form of archival for the general public within the decade.”

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China needs this data to tailor covid 20 to kill more of us.
06-05-2021 10:38 AM
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umbluegray Offline
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RE: DNA Data Storage Is About To Go Viral
DNA data is mind-boggling complex.

The more we learn the more we realize that random changes to DNA structure does not produce new data but actually degrades it.

The odds of random changes to DNA producing more complex systems is so vast that there has not been enough time since the origin of the universe to give us the life forms we have today.


The more we learn the more we realize that in the beginning God.



06-05-2021 11:01 AM
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Danforth Offline
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Post: #5
RE: DNA Data Storage Is About To Go Viral
This was only a matter of time.

The question now is what are people going to do with this information?
06-08-2021 09:37 AM
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VA49er Offline
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Post: #6
RE: DNA Data Storage Is About To Go Viral
(06-08-2021 09:37 AM)Danforth Wrote:  This was only a matter of time.

The question now is what are people going to do with this information?

Well, if they had any sense, they'd stop giving their DNA away for free to companies like 23AndMe and AncestryDNA. That DNA isn't going to stay "private" forever.
06-08-2021 10:30 AM
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RE: DNA Data Storage Is About To Go Viral
(06-08-2021 10:30 AM)VA49er Wrote:  
(06-08-2021 09:37 AM)Danforth Wrote:  This was only a matter of time.

The question now is what are people going to do with this information?

Well, if they had any sense, they'd stop giving their DNA away for free to companies like 23AndMe and AncestryDNA. That DNA isn't going to stay "private" forever.

It isn't private now. They sell your information already.
06-08-2021 11:01 AM
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stinkfist Online
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RE: DNA Data Storage Is About To Go Viral
I find all this ironic…

if intelligent design, then why are us simple, yet supposed ‘by design’ creatures trying to develop a better one…

@oxymoron

all I see is an attempt to quantify…it’s akin to continually developing communication and building via numbers + letters, in digital/molecular fashion…

make no mistake, biology will meet nano-tech one day….at that point, the concept of god will become the remainder of such…

#frankenstein
06-08-2021 12:21 PM
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Danforth Offline
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Post: #9
RE: DNA Data Storage Is About To Go Viral
(06-08-2021 11:01 AM)BartlettTigerFan Wrote:  
(06-08-2021 10:30 AM)VA49er Wrote:  
(06-08-2021 09:37 AM)Danforth Wrote:  This was only a matter of time.

The question now is what are people going to do with this information?

Well, if they had any sense, they'd stop giving their DNA away for free to companies like 23AndMe and AncestryDNA. That DNA isn't going to stay "private" forever.

It isn't private now. They sell your information already.

I never understood why people need to know this stuff anyway.

I mean it's not like people are gonna treat me any different if they find out I'm 10% Irish.
06-08-2021 12:59 PM
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umbluegray Offline
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RE: DNA Data Storage Is About To Go Viral
(06-08-2021 12:59 PM)Danforth Wrote:  
(06-08-2021 11:01 AM)BartlettTigerFan Wrote:  
(06-08-2021 10:30 AM)VA49er Wrote:  
(06-08-2021 09:37 AM)Danforth Wrote:  This was only a matter of time.

The question now is what are people going to do with this information?

Well, if they had any sense, they'd stop giving their DNA away for free to companies like 23AndMe and AncestryDNA. That DNA isn't going to stay "private" forever.

It isn't private now. They sell your information already.

I never understood why people need to know this stuff anyway.

I mean it's not like people are gonna treat me any different if they find out I'm 10% Irish.

Well, if you have 1/1000th drop of, say, Indian blood, then you can get all kinds of perks.
06-08-2021 01:21 PM
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VA49er Offline
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Post: #11
RE: DNA Data Storage Is About To Go Viral
(06-08-2021 12:59 PM)Danforth Wrote:  
(06-08-2021 11:01 AM)BartlettTigerFan Wrote:  
(06-08-2021 10:30 AM)VA49er Wrote:  
(06-08-2021 09:37 AM)Danforth Wrote:  This was only a matter of time.

The question now is what are people going to do with this information?

Well, if they had any sense, they'd stop giving their DNA away for free to companies like 23AndMe and AncestryDNA. That DNA isn't going to stay "private" forever.

It isn't private now. They sell your information already.

I never understood why people need to know this stuff anyway.

I mean it's not like people are gonna treat me any different if they find out I'm 10% Irish.

For most, it's a curiosity thing. Eventually, it will be used to determine insurance eligibity, costs, etc... amongst other things.
06-08-2021 01:28 PM
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RE: DNA Data Storage Is About To Go Viral
(06-08-2021 01:28 PM)VA49er Wrote:  
(06-08-2021 12:59 PM)Danforth Wrote:  
(06-08-2021 11:01 AM)BartlettTigerFan Wrote:  
(06-08-2021 10:30 AM)VA49er Wrote:  
(06-08-2021 09:37 AM)Danforth Wrote:  This was only a matter of time.

The question now is what are people going to do with this information?

Well, if they had any sense, they'd stop giving their DNA away for free to companies like 23AndMe and AncestryDNA. That DNA isn't going to stay "private" forever.

It isn't private now. They sell your information already.

I never understood why people need to know this stuff anyway.

I mean it's not like people are gonna treat me any different if they find out I'm 10% Irish.

For most, it's a curiosity thing. Eventually, it will be used to determine insurance eligibity, costs, etc... amongst other things.

it’s called @actions——>>>consequences
(This post was last modified: 06-08-2021 01:48 PM by stinkfist.)
06-08-2021 01:47 PM
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ericsrevenge76 Online
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RE: DNA Data Storage Is About To Go Viral
(06-05-2021 10:18 AM)TigerBlue4Ever Wrote:  What a bizarre world, nay, universe, nay, existence we inhabit. I understood very little of that.


For those who read their Bible, things like this are a sure sign we are at the end and this is likely the final generation before Christ returns.

Non believers will scoff and mock that, but all they do is fulfill scripture without even realizing it.

“In the last times there will be scoffers who will follow after their own ungodly desires.” These are the ones who cause divisions, who are worldly and devoid of the Spirit.." Jude 1:18-19
06-08-2021 02:51 PM
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RE: DNA Data Storage Is About To Go Viral
(06-08-2021 01:21 PM)umbluegray Wrote:  
(06-08-2021 12:59 PM)Danforth Wrote:  
(06-08-2021 11:01 AM)BartlettTigerFan Wrote:  
(06-08-2021 10:30 AM)VA49er Wrote:  
(06-08-2021 09:37 AM)Danforth Wrote:  This was only a matter of time.

The question now is what are people going to do with this information?

Well, if they had any sense, they'd stop giving their DNA away for free to companies like 23AndMe and AncestryDNA. That DNA isn't going to stay "private" forever.

It isn't private now. They sell your information already.

I never understood why people need to know this stuff anyway.

I mean it's not like people are gonna treat me any different if they find out I'm 10% Irish.

Well, if you have 1/1000th drop of, say, Indian blood, then you can get all kinds of perks.

Like getting a job at an Ivy League law school as a minority and then becoming a senator.
06-08-2021 06:25 PM
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rath v2.0 Offline
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RE: DNA Data Storage Is About To Go Viral
(06-08-2021 02:51 PM)ericsrevenge76 Wrote:  
(06-05-2021 10:18 AM)TigerBlue4Ever Wrote:  What a bizarre world, nay, universe, nay, existence we inhabit. I understood very little of that.


For those who read their Bible, things like this are a sure sign we are at the end and this is likely the final generation before Christ returns.

Non believers will scoff and mock that, but all they do is fulfill scripture without even realizing it.

“In the last times there will be scoffers who will follow after their own ungodly desires.” These are the ones who cause divisions, who are worldly and devoid of the Spirit.." Jude 1:18-19

Clearly. The people saying this for the past 1500 years must have been real kooks to have gotten it so wrong.
06-08-2021 08:14 PM
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ericsrevenge76 Online
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RE: DNA Data Storage Is About To Go Viral
(06-08-2021 08:14 PM)rath v2.0 Wrote:  
(06-08-2021 02:51 PM)ericsrevenge76 Wrote:  
(06-05-2021 10:18 AM)TigerBlue4Ever Wrote:  What a bizarre world, nay, universe, nay, existence we inhabit. I understood very little of that.


For those who read their Bible, things like this are a sure sign we are at the end and this is likely the final generation before Christ returns.

Non believers will scoff and mock that, but all they do is fulfill scripture without even realizing it.

“In the last times there will be scoffers who will follow after their own ungodly desires.” These are the ones who cause divisions, who are worldly and devoid of the Spirit.." Jude 1:18-19

Clearly. The people saying this for the past 1500 years must have been real kooks to have gotten it so wrong.


Well if you actually had any clue what you were talking about you would have known 99% of people did not have Bible, could not even read for most of the last 1500 years. End times studies were pretty much non-existent for most of the last 1500 years.

The RCC kept the Bible locked up and almost never spoke of or taught on end times studies, its was not until the great awakening in the 1800's that end times studies really became a serious thing. In fact if you knew anything about this at all you would have also known the church fathers of the 1st and 2nd centuries (Pre RCC) all wrote and taught that the church age would come to a close and Christ would return right about 2000 years after the cross. I don't know if math is your strong suit, but that is right about now.

But I know the facts and truth are meaningless to you anyways so just keep on trolling the Bible there little bud. I'm sure that will work out great for you in the end. 04-cheers
(This post was last modified: 06-08-2021 09:18 PM by ericsrevenge76.)
06-08-2021 08:53 PM
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rath v2.0 Offline
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RE: DNA Data Storage Is About To Go Viral
Here’s the good thing...if it’s the generation after you are here you’ll never know you were wrong.
06-08-2021 08:57 PM
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rath v2.0 Offline
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RE: DNA Data Storage Is About To Go Viral
Insert “Free Beer Tomorrow” sign here.
06-08-2021 08:58 PM
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ericsrevenge76 Online
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RE: DNA Data Storage Is About To Go Viral
(06-08-2021 08:57 PM)rath v2.0 Wrote:  Here’s the good thing...if it’s the generation after you are here you’ll never know you were wrong.


Actually those who are not denying Christ and the Gospel will have front row seats above for the entire thing, and be the judge and jury at the end.

What a sad existence you must live to think you will die in a few short years and your entire life was completely meaningless as you blink into total nothingness forever as if you never existed and nothing you ever said, did or felt ever mattered one iota.

No wonder you people are so miserable all the time. What a depressingly terrible perception of reality.
(This post was last modified: 06-08-2021 09:06 PM by ericsrevenge76.)
06-08-2021 09:03 PM
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Post: #20
RE: DNA Data Storage Is About To Go Viral
(06-08-2021 09:03 PM)ericsrevenge76 Wrote:  
(06-08-2021 08:57 PM)rath v2.0 Wrote:  Here’s the good thing...if it’s the generation after you are here you’ll never know you were wrong.


Actually those who are not denying Christ and the Gospel will have front row seats above for the entire thing, and be the judge and jury at the end.

What a sad existence you must live to think you will die in a few short years and your entire life was completely meaningless as you blink into total nothingness forever as if you never existed and nothing you ever said, did or felt ever mattered one iota.

No wonder you people are so miserable all the time. What a depressingly terrible perception of reality.

Eric, wouldn’t it be better that your name be written in the book of life than to try to predict the last days? Jesus says in Matthew 24:36 no one knows the hour of his return not even he himself. Only the Father knows.

Now, you could believe that the internet is a sign. It is said in Revelation that once the two witnesses had been killed every nation will gaze at their dead bodies laying in the streets for three and a half days.

The only way I can see everyone looking at their dead bodies is the internet. My two cents
06-08-2021 11:11 PM
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