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A thread to share positive news about Covid-19 Rx and vaccine developments
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TIGERCITY Offline
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Post: #321
RE: A thread to share positive news about Covid-19 Rx and vaccine developments
It's my understanding the FDA only uses studies that represents the U.S. population. For example, UK trial wouldn't have any Native Americans included.
(This post was last modified: 12-30-2020 10:18 AM by TIGERCITY.)
12-30-2020 10:13 AM
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TIGERCITY Offline
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Post: #322
RE: A thread to share positive news about Covid-19 Rx and vaccine developments
(12-30-2020 08:37 AM)Tiger1983 Wrote:  The Oxford, AstraZeneca vaccine obtains U.K. approval. Sufficient data for FDA approval may be available by February.

https://www.wsj.com/articles/oxford-astr...1609317308

1. Two shots are required.

2. AstraZeneca’s vaccine uses a traditional vaccine strategy by placing a weak virus strain from a chimp into the body which then causes an immune response.

3. The shot - vetted for safety - s 62% effective compared to 95% for Pfizer and 94% for Moderna. However, a small subset were given a half dose followed by a full dose which resulted in 90% effectiveness. Scientists say more study is needed to explain the 90% figure.

4. The AstraZeneca, Pfizer, and Moderna vaccines should be effective against the newly identified CV-19 variant.

An aside: What is the issue with using UK data for the FDA evaluation? The UK has an advanced medical system and first rate medical research capacity and is a democracy. They would not unleash an unsafe drug upon the public.

Also 100% efficacious against severe disease.

A couple of days ago Astrazeneca's CEO or someone like that stated that the vaccine will be as efficacious as Moderna and Pfizer vaccines which means by 95%. They said the data would be published later. The issue apparently was the timing between the two doses.
12-30-2020 10:24 AM
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TIGERCITY Offline
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Post: #323
RE: A thread to share positive news about Covid-19 Rx and vaccine developments
(12-31-2020 11:26 AM)TIGERCITY Wrote:  https://mobile.twitter.com/MRC_Outbreak/...variant%2F


This is the latest on the variant, the deletion that has increased transmissibility first discovered in the UK. The variant increases transmissibility over the non variant by 0.4 to 0.7 --- so the reproductive number for this is 1.4 to 1.8. For whatever reason it is infecting under-20s the most
12-31-2020 11:45 AM
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TIGERCITY Offline
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Post: #324
RE: A thread to share positive news about Covid-19 Rx and vaccine developments
(12-31-2020 11:45 AM)TIGERCITY Wrote:  
(12-31-2020 11:26 AM)TIGERCITY Wrote:  https://mobile.twitter.com/MRC_Outbreak/...variant%2F


This is the latest on the variant, the deletion that has increased transmissibility first discovered in the UK. The variant increases transmissibility over the non variant by 0.4 to 0.7 --- so the reproductive number for this is 1.4 to 1.8. For whatever reason it is infecting under-20s the most

And right on cue the variant has been found in California and Colorado. The FDA needs to get off his ass and approve the AstraZeneca vaccine.

https://www.nytimes.com/2020/12/30/healt...orado.html
12-31-2020 02:35 PM
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Tiger1983 Offline
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Post: #325
RE: A thread to share positive news about Covid-19 Rx and vaccine developments
“US officials are considering giving people 2 half doses of Moderna's COVID-19 shot to speed up rollout, vaccine chief Slaoui says”

https://www.google.com/amp/s/www.busines...21-1%3famp

Evidence apparently exists that half doses are as effective as full doses in folks between 18 and 55. FDA approval is needed.
01-04-2021 03:20 PM
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Tiger1983 Offline
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Post: #326
RE: A thread to share positive news about Covid-19 Rx and vaccine developments
“Covid-19 immunity likely lasts for years” for both those vaccinated and recovered.

https://www.google.com/amp/s/www.technol...years/amp/
01-07-2021 05:41 PM
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Tiger1983 Offline
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Post: #327
RE: A thread to share positive news about Covid-19 Rx and vaccine developments


Although the tweet is directed to Tennesseans, I surmise the treatment’s efficacy transcends state lines. :)
01-08-2021 03:13 PM
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Tiger1983 Offline
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Post: #328
RE: A thread to share positive news about Covid-19 Rx and vaccine developments

According to the article, early data shows a 33% decline after two weeks. Israel has vaccinated about a 1/4th the nation - the highest world rate. Finally, the side effects are no worse than other vaccinations.
(This post was last modified: 01-16-2021 12:06 AM by Tiger1983.)
01-15-2021 11:58 PM
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TIGERCITY Offline
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Post: #329
RE: A thread to share positive news about Covid-19 Rx and vaccine developments
This Nature article describes the spread of SARS CoV2 and concludes that it will likely remain in the world population resulting in almost everyone eventually either getting the disease or gaining immunity through vaccination. After which reinfection and viral shedding (spread) remain. Those whos immune systems have previously been exposed to likely have common cold like symptoms. Compares this virus to the other four endemic common cold coronaviruses and the likely similar history of those viruses. Predicts a similar path for SARS CoV2.

https://www.nature.com/articles/s41577-020-00493-9
01-16-2021 08:41 AM
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goodknightfl Offline
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Post: #330
RE: A thread to share positive news about Covid-19 Rx and vaccine developments
(01-08-2021 03:13 PM)Tiger1983 Wrote:  

Although the tweet is directed to Tennesseans, I surmise the treatment’s efficacy transcends state lines. :)

hard to say. Tennesseans ar a breed all their own.
01-16-2021 09:12 AM
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TIGERCITY Offline
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Post: #331
RE: A thread to share positive news about Covid-19 Rx and vaccine developments
(01-16-2021 08:41 AM)TIGERCITY Wrote:  This Nature article describes the spread of SARS CoV2 and concludes that it will likely remain in the world population resulting in almost everyone eventually either getting the disease or gaining immunity through vaccination. After which reinfection and viral shedding (spread) remain. Those whos immune systems have previously been exposed to likely have common cold like symptoms. Compares this virus to the other four endemic common cold coronaviruses and the likely similar history of those viruses. Predicts a similar path for SARS CoV2.

https://www.nature.com/articles/s41577-020-00493-9

In a similar vein this study looked at 43,000 individuals who had a previous infection. The chances of re-infection was shown to be 0.1% (in this study.)

https://www.medrxiv.org/content/10.1101/...21249731v1
(This post was last modified: 01-16-2021 01:25 PM by TIGERCITY.)
01-16-2021 01:24 PM
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Tiger1983 Offline
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Post: #332
RE: A thread to share positive news about Covid-19 Rx and vaccine developments
Johnson & Johnson’s vaccine update:

1. It is in a late-stage study of 45,000 volunteers.

2. Results of the late stage study could be available within two weeks.

3. It requires only one shot and may be shipped unfrozen.

4. If approved by regulators, distribution may start in late February.

https://www.bostonglobe.com/2021/01/16/n...ssion=true

And


(This post was last modified: 01-18-2021 08:54 PM by Tiger1983.)
01-17-2021 11:20 PM
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