Hey,
A couple ideas on what you like to do helps us give advice. Otherwise, we tell you what we like to do. You can actually do me a return. I'll be a spit from your this summer (Exeter) and could use some tips. Running parks/camping/ sea food, would be of some interest.
Toledo City Paper has a good overview of nightlife, which will be timely.
Our Downtown isn't so big that anywhere is far from anywhere else. It's not near campus though. If you'll be staying downtown, the place for jazz would be Murphy's. There are a few others around town will give good measure.
Dance Clubs downtown, I don't know much about.
If you're a bit harder, someone mentioned Frankie's on the Eastside, just across the bridge. Very organic, in the neighborhood kind of place. They bring in local and traveling bands. Hip Hop, Rock, whatever...
"Must Eats" Eastside again. I'm not biased, really I'm not. Tony Packos, the original. Again, organic and original. Visitors like the place so it's not just a local legend. There is one downtown but next time your watching M*A*S*H and they mention Tony Packos, you won't really be able to say you've been there. The one downtown, it's the food without the atmosphere.
If museum or local art is your thing, you might be extremely surprised at what we got. We just stole Dartmouth's Director because the Walmart Walton's stole ours for a new museum they're planning, just to give you a measure of how influenctial our museum is.
If you're downtown, there might also be a ball game. Mud Hens stadium, rated one of the best in the minor leagues is in the center of town. Fun place. Huntington Center/arena, is also downtown. Keep an eye on The City Paper for what might be playing.
Another place downtown that has Broadway and Symphony type shows is the Valentine Theatre.