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Bacteria cooperating to defeat antibiotics - Printable Version

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Bacteria cooperating to defeat antibiotics - bullet - 10-07-2019 08:53 PM

https://www.livescience.com/microbe-spreads-antibiotic-resistance-to-bacteria.html

"...The patient had contracted the well-known superbug MRSA (methicillin-resistant Staphylococcus aureus). So the medical team turned to one of the "last line of defence" antibiotics, the powerful compound vancomycin. This strain of MRSA originally had no natural defence against vancomycin, but by August that year it had become resistant, rendering the treatment ineffective.

Scientists would later uncover that rather than acquiring resistance through a simple mutation, the MRSA had instead been gifted a huge chunk of new DNA. Within this string of donated genetic code were the instructions for proteins that would keep the bacteria safe from the destructive work of the antibiotic. MRSA had been dealt a winning hand, but where had this DNA come from?

Enter Enterococcus faecalis. This bug is typically described as a commensal bacterium (one of our "good bacteria"), which lives happily in our guts causing no harm....

Antibiotics perform a critical role in modern medicine. They're used routinely to treat infectious disease, administered pre-emptively after surgery, and have contributed to raising the average life expectancy by an average of 20 years across the globe. This makes tackling antibiotic resistance one of the most pressing issues faced by our species today. Yet, in bacteria such as faecalis, scientists have discovered microbes colluding to escalate the danger presented by evolved antibiotic resistance...."


RE: Bacteria cooperating to defeat antibiotics - stinkfist - 10-07-2019 08:58 PM

there's a worthy Nobel of Medicine winner....


RE: Bacteria cooperating to defeat antibiotics - banker - 10-07-2019 09:39 PM

(10-07-2019 08:58 PM)stinkfist Wrote:  there's a worthy Nobel of Medicine winner....

For the germs.


RE: Bacteria cooperating to defeat antibiotics - stinkfist - 10-07-2019 09:53 PM

(10-07-2019 09:39 PM)banker Wrote:  
(10-07-2019 08:58 PM)stinkfist Wrote:  there's a worthy Nobel of Medicine winner....

For the germs.

caught that sarc, eh? 03-wink


RE: Bacteria cooperating to defeat antibiotics - JRsec - 10-07-2019 09:53 PM

(10-07-2019 08:53 PM)bullet Wrote:  https://www.livescience.com/microbe-spreads-antibiotic-resistance-to-bacteria.html

"...The patient had contracted the well-known superbug MRSA (methicillin-resistant Staphylococcus aureus). So the medical team turned to one of the "last line of defence" antibiotics, the powerful compound vancomycin. This strain of MRSA originally had no natural defence against vancomycin, but by August that year it had become resistant, rendering the treatment ineffective.

Scientists would later uncover that rather than acquiring resistance through a simple mutation, the MRSA had instead been gifted a huge chunk of new DNA. Within this string of donated genetic code were the instructions for proteins that would keep the bacteria safe from the destructive work of the antibiotic. MRSA had been dealt a winning hand, but where had this DNA come from?

Enter Enterococcus faecalis. This bug is typically described as a commensal bacterium (one of our "good bacteria"), which lives happily in our guts causing no harm....

Antibiotics perform a critical role in modern medicine. They're used routinely to treat infectious disease, administered pre-emptively after surgery, and have contributed to raising the average life expectancy by an average of 20 years across the globe. This makes tackling antibiotic resistance one of the most pressing issues faced by our species today. Yet, in bacteria such as faecalis, scientists have discovered microbes colluding to escalate the danger presented by evolved antibiotic resistance...."

Thankfully we are now several generations past vancomycin, but unfortunately bacteria are great at adaptations and are survivors. Once again from the moment you are born life is out to get you. I've known too many who weakened tremendously or eventually succumbed because of MRSA or their weakened condition from it. Clostridium Difficile is another big killer.


RE: Bacteria cooperating to defeat antibiotics - stinkfist - 10-07-2019 10:03 PM

(10-07-2019 09:53 PM)JRsec Wrote:  
(10-07-2019 08:53 PM)bullet Wrote:  https://www.livescience.com/microbe-spreads-antibiotic-resistance-to-bacteria.html

"...The patient had contracted the well-known superbug MRSA (methicillin-resistant Staphylococcus aureus). So the medical team turned to one of the "last line of defence" antibiotics, the powerful compound vancomycin. This strain of MRSA originally had no natural defence against vancomycin, but by August that year it had become resistant, rendering the treatment ineffective.

Scientists would later uncover that rather than acquiring resistance through a simple mutation, the MRSA had instead been gifted a huge chunk of new DNA. Within this string of donated genetic code were the instructions for proteins that would keep the bacteria safe from the destructive work of the antibiotic. MRSA had been dealt a winning hand, but where had this DNA come from?

Enter Enterococcus faecalis. This bug is typically described as a commensal bacterium (one of our "good bacteria"), which lives happily in our guts causing no harm....

Antibiotics perform a critical role in modern medicine. They're used routinely to treat infectious disease, administered pre-emptively after surgery, and have contributed to raising the average life expectancy by an average of 20 years across the globe. This makes tackling antibiotic resistance one of the most pressing issues faced by our species today. Yet, in bacteria such as faecalis, scientists have discovered microbes colluding to escalate the danger presented by evolved antibiotic resistance...."

Thankfully we are now several generations past vancomycin, but unfortunately bacteria are great at adaptations and are survivors. Once again from the moment you are born life is out to get you. I've known too many who weakened tremendously or eventually succumbed because of MRSA or their weakened condition from it. Clostridium Difficile is another big killer.

it's interesting looking backwards en macro how our species has mutated/evolved/survived over time....

it's easily why the concept of any deity has ever existed in whatever form....

I think you're about same age as my parents.....I told them as a tyke how amazing they were to inherit the greatest period in time relative to ethics, incentive, and value in the history of mankind....

they looked at me like I was crazy....sometimes they still do....I still laugh at 'em and with 'em...

#boomerYaYa


RE: Bacteria cooperating to defeat antibiotics - SoMs Eagle - 10-07-2019 10:33 PM

How much longer until it’s KMAGYOYO?
The population will be thinned again but who knows from which direction....


RE: Bacteria cooperating to defeat antibiotics - stinkfist - 10-07-2019 10:39 PM

(10-07-2019 10:33 PM)SoMs Eagle Wrote:  How much longer until it’s KMAGYOYO?
The population will be thinned again but who knows from which direction....

once the dickbrains finally push the final stupid button after the boomers die off....that's my best guess....


RE: Bacteria cooperating to defeat antibiotics - JRsec - 10-07-2019 11:58 PM

(10-07-2019 10:33 PM)SoMs Eagle Wrote:  How much longer until it’s KMAGYOYO?
The population will be thinned again but who knows from which direction....

Most likely it will happen from one or a combination of the following:
1. Lack of potable water leading to the use of gray or dirty water causing cholera outbreaks and massive dysentery.

2. Starvation as petroleum passes peak and energy consumption negates the use of petroleum for fertilizer. The earth's population of humans was fairly static for several millennia at around 3.5 to 4 billion depending upon wars, plagues, etc, which caused it to fluctuate. Then around 1885 forward with the introduction of petroleum based fertilizer yields on arable land were increased as much as 20 fold enabling the earth to feed many more. Now that the population has passed 8 billion when fertilizer returns to being potassium and nitrogen found in the amounts typically yielded by composting the food production capacity will again drop.

3. Pandemic like the 1918 Spanish Influenza.

4. The fallout of nuclear war, but not between super powers, but rather developing 3rd world regional powers simply poisons the planet leading to massive amounts of thyroid and other kinds of cancer.

5. Something from space, asteroid, comet, pulsar gamma ray blast, massive solar flare impact, or something unforeseen.

But most likely it will be one of the first 3.


RE: Bacteria cooperating to defeat antibiotics - 49RFootballNow - 10-08-2019 08:57 AM

This reminds me of an episode of Cells at Work.


RE: Bacteria cooperating to defeat antibiotics - SoMs Eagle - 10-08-2019 01:19 PM

(10-07-2019 11:58 PM)JRsec Wrote:  
(10-07-2019 10:33 PM)SoMs Eagle Wrote:  How much longer until it’s KMAGYOYO?
The population will be thinned again but who knows from which direction....

Most likely it will happen from one or a combination of the following:
1. Lack of potable water leading to the use of gray or dirty water causing cholera outbreaks and massive dysentery.

2. Starvation as petroleum passes peak and energy consumption negates the use of petroleum for fertilizer. The earth's population of humans was fairly static for several millennia at around 3.5 to 4 billion depending upon wars, plagues, etc, which caused it to fluctuate. Then around 1885 forward with the introduction of petroleum based fertilizer yields on arable land were increased as much as 20 fold enabling the earth to feed many more. Now that the population has passed 8 billion when fertilizer returns to being potassium and nitrogen found in the amounts typically yielded by composting the food production capacity will again drop.

3. Pandemic like the 1918 Spanish Influenza.

4. The fallout of nuclear war, but not between super powers, but rather developing 3rd world regional powers simply poisons the planet leading to massive amounts of thyroid and other kinds of cancer.

5. Something from space, asteroid, comet, pulsar gamma ray blast, massive solar flare impact, or something unforeseen.

But most likely it will be one of the first 3.

A coronal mass ejection frying electronics would instantly, well, within a week or two kill billions of people. Then the remaining people would probably kill another billion.